Chang Jiang Scholar
School of Chemistry and Chemical Engineering

State Key Laboratory of Analytical Chemistry for Life Science
Nanjing University
Nanjing 210023, P. R. CHINA
Tel: 86-25-89680349
Email: yitaolong@nju.edu.cn
Office: Room G224, Chemical Building


  • Single Molecule Interface, Electrochemically Nanoconfined Space, Nanopore Single Molecule Analysis, Nanoelectrochemistry, in-situ Spectroelectrochemistry


Ph.D., 1996-1998  Bioelectrochemistry, Nanjing University, Nanjing, CHINA
            Under supervision of Professor Hong-Yuan Chen
M.Sc., 1993-1996  Analytical Chemistry, Nanjing University, Nanjing, CHINA
            Under supervision of Professor Hong-Yuan Chen
B.Sc.,  1985-1989  Chemistry, Shandong University, Jinan, CHINA

Professional experience

  • 2019-            Professor, School of Chemistry and Chemical Engineering, Nanjing University, CHINA

  • 2014-            Visiting Professor, Department of Chemistry, University of Western Ontario, CANADA

  • 2013-            Honorary Visiting Professor, School of Chemistry, University of Birmingham, UK

  • 2011-            Visiting Professor, Department of Chemistry, University of Bath, UK

  • 2007-2018    Distinguished Professor, School of Chemistry & Molecular Engineering, East China University of Science and Technology (ECUST), CHINA

  • 2006-2007    Senior Research Scientist, Departments of Chemistry & Bioengineering,Biomolecular Nanotechnology                                             Center, Berkeley Sensor & Actuator Center,University of California, Berkeley, USA

  • 2001-2006    Research Associate, Departments of Chemistry and Biochemistry, University of Saskatchewan;                                                           Department of Electrical & Computer Engineering, University of Alberta, CANADA

  • 2001             Research AssociateÉcole Nationale Supérieure de Chimie de Paris (ENSCP), FRANCE 

  • 1999-2001    Postdoctoral  Fellow, Institute of Applied Physical Chemistry, Heidelberg University, GERMANY


  • Editorial Board Member for Chemical Reviews, 2022-

  • Associate Editor for Chemical Science, 2019-

  • Associate Editor for 《高等学校化学学报》, 2019-

  • Associate Editor for Research, 2018-

  • Editorial Board Member for 《电化学》, 2017-

  • Editorial Board Member for ChemEletrocChem, 2017-

  • Associate Editor for ACS Sensors, 2015-2018

  • Editorial Board Member for 《分析化学》, 2015-

  • Editorial Board Member for RSC Advances, 2013-2016

  • Editorial Board Member for RSC Advances, 2013-

  • Editorial Board Member for 《化学学报》, 2012-

  • Editorial Board Member for Theranostics, 2011-

  • Editorial Board Member for Microchimica Acta, 2011-

  • Editorial Board Member for Chemistry Central Journal, Section Editor in analytical chemistry, 2011-2018

Selected honors & Awards

  • First Prize of Science & Technology Award of China Association for Instrumental Analysis (2022)

  • The Power List 2020: Around the World in 60 Scientists (2020)

  • Fellow of International Society of Electrochemistry (ISE) (2020)

  • Liang Shuquan Award for Basic Research in Analytical Chemistry (2018)

  • Grand Prize of Science & Technology Award of China Association for Instrumental Analysis (2017)

  • First Prize of Shanghai Natural Science Award (2016)

  • Distinguished Visitor Fund of University of Alberta (2015)

  • Outstanding Overseas Chinese Contribution Award (2014)

  • Fellow of the Royal Society of Chemistry (FRSC) (2013)

  • Chang Jiang Scholar (2012)

  • National Science Fund for Distinguished Young Scholars (2011)

  • Shanghai Pujiang Scholar (2009)

  • Shanghai Eastern Scholar (2009)

Selected Publications (*Corresponding author) 

1. Jie Jiang, Meng-Yin Li, Xue-Yuan Wu, Yi-Lun Ying, Huan-Xing Han, and Yi-Tao Long* (2023). Protein nanopore reveals the renin–angiotensin system crosstalk with single-amino-acid resolution, Nature Chemistry, 1-9. DOI: 10.1038/s41557-023-01139-8.

2. Mengjie Chen, Si-Min Lu*, Hao-Wei Wang, and Yi-Tao Long* (2023). Monitoring Photoinduced Interparticle Chemical Communication In situ, Angewandte Chemie International Edition, 135(10). DOI: 10.1002/anie.202215631.

3. Yi-Lun Ying, Zheng-Li Hu, Shengli Zhang, Yujia Qing, Alessio Fragasso, Giovanni Maglia*, Amit Meller*, Hagan Bayley*, Cees Dekker*, and Yi-Tao Long* (2022). Nanopore-based technologies beyond DNA sequencing, Nature Nanotechnology, 17(11): 1136-1146. DOI: 10.1038/s41565-022-01193-2.

4. Kai-Li Xin, Zheng-Li Hu*, Shao-Chuang Liu, Xin-Yi Li, Jun-Ge Li, Hongyan Niu, Yi-Lun Ying, and Yi-Tao Long* (2022). 3D Blockage Mapping for Identifying Familial Point Mutations in Single Amyloid-β Peptides with a Nanopore, Angewandte Chemie International Edition, 61(44). DOI: 10.1002/anie.202209970.

5. Jiajun Wang, Jigneshkumar Dahyabhai Prajapati, Fan Gao, Yi-Lun Ying*, Ulrich Kleinekathöfer, Mathias Winterhalter*, and Yi-Tao Long (2022). Identification of Single Amino Acid Chiral and Positional Isomers Using an Electrostatically Asymmetric Nanopore, Journal of the American Chemical Society, 144, 33, 15072–15078. DOI: 10.1021/jacs.2c03923.

6. Xin-Yi Li, Yi-Lun Ying, Xi-Xin Fu, Yong-Jing Wan, and Yi-Tao Long* (2021). Single-Molecule Frequency Fingerprint for Ion Interaction Networks in a Confined Nanopore, Angewandte Chemie International Edition, 60(46), 24582-24587. DOI: 10.1002/anie.202108226.

7. Si-Min Lu, Jian-Fu Chen, Yue-Yi Peng, Wei Ma, Hui Ma, Hai-Feng Wang, Peijun Hu, and Yi-Tao Long* (2021). Understanding the Dynamic Potential Distribution at the Electrode Interface by Stochastic Collision Electrochemistry, Journal of the American Chemical Society, 143(32), 12428-12432. DOI: 10.1021/jacs.1c02588.

8. Meng-Yin Li, Yi-Lun Ying, Jie Yu, Shao-Chuang Liu, Ya-Qian Wang, Shuang Li, Yi-Tao Long* (2021). Revisiting the Origin of Nanopore Current Blockage for Volume Difference Sensing at the Atomic Level, JACS Au, 1(7), 967-976. DOl: 10.1021/jacsau.1c00109.

9. Zheng-Li Hu, Ming-Zhu Huo, Yi-Lun Ying, and Yi-Tao Long* (2021). Biological Nanopore Approach for Single-Molecule Protein Sequencing, Angewandte Chemie International Edition, 133(27), 14862-14873. DOI: 10.1002/anie.202013462.

10. Hui Ma, Jian-Fu Chen, Hai-Feng Wang, Pei-Jun Hu, Wei Ma, and Yi-Tao Long* (2020). Exploring dynamic interactions of single nanoparticles at interfaces for surface-confined electrochemical behavior and size measurement, Nature Communications, 11(1), 2307. DOI: 10.1038/s41467-020-16149-0.


11. Yi-Lun Ying, Yi-Tao Long* (2019). Nanopore-Based Single-Biomolecule Interfaces: From Information to Knowledge, Journal of the American Chemical SocietyDOI: 10.1021/jacs.8b11970


12. Yi-Lun Ying†, Yong-Xu Hu†, Rui Gao, Ru-Jia Yu, Zhen Gu, Luke P. Lee, Yi-Tao Long* (2018). Asymmetric Nanopore Electrode-Based Amplification for Electron Transfer Imaging in Live Cells, Journal of the American Chemical Society, 140(16), 5385-5392. DOI: 10.1021/jacs.7b12106 


13. Rui Gao, Yi-Lun Ying,* Yuan-Jie Li, Yong-Xu Hu, Ru-Jia Yu, Yao Lin, Yi-Tao Long* (2018). A 30 nm Nanopore Electrode: Facile Fabrication and Direct Revealing of the Intrinsic Feature in Single Nanoparticle Collision,Angewandte Chemie International Edition, 57(4), 1011-1015. DOI: 10.1002/anie.201710201 


14. Chao Jing, Zhen Gu, Tao Xie, Yi-Tao Long* (2016). Color-Coded Imaging of Electrochromic Process at Single Nanoparticle Level, Chemical Science, 7(8), 5347-5351. DOI: 10.1039/C6SC00903D 


15. Yi-Lun Ying, Zhifeng Ding, Dong-Ping Zhan, Yi-Tao Long* (2017). Advanced Electroanalytical Chemistry at Nanoelectrodes, Chemical Science, 8(5), 3338-3348. DOI: 10.1039/C7SC00433H

16. Chan Cao, Yi-Lun Ying, Zheng-Li Hu, Dong-Fang Liao, He Tian, Yi-Tao Long* (2016). Discrimination of Oligonucleotides of Different Lengths with a Wild-type Aerolysin Nanopore, Nature Nanotechnology, 11(8), 713-718.DOI: 10.1038/nnano.2016.66 


17. Chan Cao†, Dong-Fang Liao†, Jie Yu, He Tian, Yi-Tao Long* (2017). Construction of an Aerolysin Nanopore in a Lipid Bilayer for Single-Oligonucleotide AnalysisNature Protocols, 12(9), 1901-1911. (Cover) DOI: 10.1038/nprot.2017.077 


18. Chan Cao, Yi-Tao Long* (2018). Biological Nanopores: Confined Spaces for Electrochemical Single-Molecule Analysis, Accounts of Chemical Research, 51(2), 331-341. DOI: 10.1021/acs.accounts.7b00143 


19. Chan Cao, Meng-Yin Li, Nuria Cirauqui, Ya-Qian Wang, Matteo Dal Peraro*, He Tian, Yi-Tao Long* (2018). Mapping the Sensing Spots of Aerolysin for Single Oligonucleotides Analysis, Nature Communications, 9(1), 2823-2830. DOI: 10.1038/s41467-018-05108-5 


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