Yi-Tao LONG
Chang Jiang Scholar
School of Chemistry and Chemical Engineering
State Key Laboratory of Analytical Chemistry for Life Science
Nanjing University
Nanjing 210023, P. R. CHINA
Tel: 86-25-89680349
Email: yitaolong@nju.edu.cn
Office: Room G224, Chemical Building
RESEARCH INTERESTS
Single Molecule Interface, Electrochemically Nanoconfined Space, Nanopore Single Molecule Analysis, Nanoelectrochemistry, in-situ Spectroelectrochemistry
Education
Ph.D., 1996-1998 Bioelectrochemistry, Nanjing University, Nanjing, CHINA
Under supervision of Professor Hong-Yuan Chen
M.Sc., 1993-1996 Analytical Chemistry, Nanjing University, Nanjing, CHINA
Under supervision of Professor Hong-Yuan Chen
B.Sc., 1985-1989 Chemistry, Shandong University, Jinan, CHINA
Professional experience
2019- Professor, School of Chemistry and Chemical Engineering, Nanjing University, CHINA
2014- Visiting Professor, Department of Chemistry, University of Western Ontario, CANADA
2013- Honorary Visiting Professor, School of Chemistry, University of Birmingham, UK
2011- Visiting Professor, Department of Chemistry, University of Bath, UK
2007-2018 Distinguished Professor, School of Chemistry & Molecular Engineering, East China University of Science and Technology (ECUST), CHINA
2006-2007 Senior Research Scientist, Departments of Chemistry & Bioengineering,Biomolecular Nanotechnology Center, Berkeley Sensor & Actuator Center,University of California, Berkeley, USA
2001-2006 Research Associate, Departments of Chemistry and Biochemistry, University of Saskatchewan; Department of Electrical & Computer Engineering, University of Alberta, CANADA
2001 Research Associate, École Nationale Supérieure de Chimie de Paris (ENSCP), FRANCE
1999-2001 Postdoctoral Fellow, Institute of Applied Physical Chemistry, Heidelberg University, GERMANY
PUBLIC & PROFESSIONAL SERVICEs
Editorial Board Member for Chemical Reviews, 2022-
Associate Editor for Chemical Science, 2019-
Associate Editor for 《高等学校化学学报》, 2019-
Associate Editor for Research, 2018-
Editorial Board Member for 《电化学》, 2017-
Editorial Board Member for ChemEletrocChem, 2017-
Associate Editor for ACS Sensors, 2015-2018
Editorial Board Member for 《分析化学》, 2015-
Editorial Board Member for RSC Advances, 2013-2016
Editorial Board Member for RSC Advances, 2013-
Editorial Board Member for 《化学学报》, 2012-
Editorial Board Member for Theranostics, 2011-
Editorial Board Member for Microchimica Acta, 2011-
Editorial Board Member for Chemistry Central Journal, Section Editor in analytical chemistry, 2011-2018
Selected honors & Awards
First Prize of Science & Technology Award of China Association for Instrumental Analysis (2022)
The Power List 2020: Around the World in 60 Scientists (2020)
Fellow of International Society of Electrochemistry (ISE) (2020)
Liang Shuquan Award for Basic Research in Analytical Chemistry (2018)
Grand Prize of Science & Technology Award of China Association for Instrumental Analysis (2017)
First Prize of Shanghai Natural Science Award (2016)
Distinguished Visitor Fund of University of Alberta (2015)
Outstanding Overseas Chinese Contribution Award (2014)
Fellow of the Royal Society of Chemistry (FRSC) (2013)
Chang Jiang Scholar (2012)
National Science Fund for Distinguished Young Scholars (2011)
Shanghai Pujiang Scholar (2009)
Shanghai Eastern Scholar (2009)
Selected Publications (*Corresponding author)
1. Jie Jiang, Meng-Yin Li, Xue-Yuan Wu, Yi-Lun Ying, Huan-Xing Han, and Yi-Tao Long* (2023). Protein nanopore reveals the renin–angiotensin system crosstalk with single-amino-acid resolution, Nature Chemistry, 1-9. DOI: 10.1038/s41557-023-01139-8.
2. Mengjie Chen, Si-Min Lu*, Hao-Wei Wang, and Yi-Tao Long* (2023). Monitoring Photoinduced Interparticle Chemical Communication In situ, Angewandte Chemie International Edition, 135(10). DOI: 10.1002/anie.202215631.
3. Yi-Lun Ying, Zheng-Li Hu, Shengli Zhang, Yujia Qing, Alessio Fragasso, Giovanni Maglia*, Amit Meller*, Hagan Bayley*, Cees Dekker*, and Yi-Tao Long* (2022). Nanopore-based technologies beyond DNA sequencing, Nature Nanotechnology, 17(11): 1136-1146. DOI: 10.1038/s41565-022-01193-2.
4. Kai-Li Xin, Zheng-Li Hu*, Shao-Chuang Liu, Xin-Yi Li, Jun-Ge Li, Hongyan Niu, Yi-Lun Ying, and Yi-Tao Long* (2022). 3D Blockage Mapping for Identifying Familial Point Mutations in Single Amyloid-β Peptides with a Nanopore, Angewandte Chemie International Edition, 61(44). DOI: 10.1002/anie.202209970.
5. Jiajun Wang, Jigneshkumar Dahyabhai Prajapati, Fan Gao, Yi-Lun Ying*, Ulrich Kleinekathöfer, Mathias Winterhalter*, and Yi-Tao Long (2022). Identification of Single Amino Acid Chiral and Positional Isomers Using an Electrostatically Asymmetric Nanopore, Journal of the American Chemical Society, 144, 33, 15072–15078. DOI: 10.1021/jacs.2c03923.
6. Xin-Yi Li, Yi-Lun Ying, Xi-Xin Fu, Yong-Jing Wan, and Yi-Tao Long* (2021). Single-Molecule Frequency Fingerprint for Ion Interaction Networks in a Confined Nanopore, Angewandte Chemie International Edition, 60(46), 24582-24587. DOI: 10.1002/anie.202108226.
7. Si-Min Lu, Jian-Fu Chen, Yue-Yi Peng, Wei Ma, Hui Ma, Hai-Feng Wang, Peijun Hu, and Yi-Tao Long* (2021). Understanding the Dynamic Potential Distribution at the Electrode Interface by Stochastic Collision Electrochemistry, Journal of the American Chemical Society, 143(32), 12428-12432. DOI: 10.1021/jacs.1c02588.
8. Meng-Yin Li, Yi-Lun Ying, Jie Yu, Shao-Chuang Liu, Ya-Qian Wang, Shuang Li, Yi-Tao Long* (2021). Revisiting the Origin of Nanopore Current Blockage for Volume Difference Sensing at the Atomic Level, JACS Au, 1(7), 967-976. DOl: 10.1021/jacsau.1c00109.
9. Zheng-Li Hu, Ming-Zhu Huo, Yi-Lun Ying, and Yi-Tao Long* (2021). Biological Nanopore Approach for Single-Molecule Protein Sequencing, Angewandte Chemie International Edition, 133(27), 14862-14873. DOI: 10.1002/anie.202013462.
10. Hui Ma, Jian-Fu Chen, Hai-Feng Wang, Pei-Jun Hu, Wei Ma, and Yi-Tao Long* (2020). Exploring dynamic interactions of single nanoparticles at interfaces for surface-confined electrochemical behavior and size measurement, Nature Communications, 11(1), 2307. DOI: 10.1038/s41467-020-16149-0.
11. Yi-Lun Ying, Yi-Tao Long* (2019). Nanopore-Based Single-Biomolecule Interfaces: From Information to Knowledge, Journal of the American Chemical Society, DOI: 10.1021/jacs.8b11970
12. Yi-Lun Ying†, Yong-Xu Hu†, Rui Gao, Ru-Jia Yu, Zhen Gu, Luke P. Lee, Yi-Tao Long* (2018). Asymmetric Nanopore Electrode-Based Amplification for Electron Transfer Imaging in Live Cells, Journal of the American Chemical Society, 140(16), 5385-5392. DOI: 10.1021/jacs.7b12106
13. Rui Gao, Yi-Lun Ying,* Yuan-Jie Li, Yong-Xu Hu, Ru-Jia Yu, Yao Lin, Yi-Tao Long* (2018). A 30 nm Nanopore Electrode: Facile Fabrication and Direct Revealing of the Intrinsic Feature in Single Nanoparticle Collision,Angewandte Chemie International Edition, 57(4), 1011-1015. DOI: 10.1002/anie.201710201
14. Chao Jing, Zhen Gu, Tao Xie, Yi-Tao Long* (2016). Color-Coded Imaging of Electrochromic Process at Single Nanoparticle Level, Chemical Science, 7(8), 5347-5351. DOI: 10.1039/C6SC00903D
15. Yi-Lun Ying, Zhifeng Ding, Dong-Ping Zhan, Yi-Tao Long* (2017). Advanced Electroanalytical Chemistry at Nanoelectrodes, Chemical Science, 8(5), 3338-3348. DOI: 10.1039/C7SC00433H
16. Chan Cao, Yi-Lun Ying, Zheng-Li Hu, Dong-Fang Liao, He Tian, Yi-Tao Long* (2016). Discrimination of Oligonucleotides of Different Lengths with a Wild-type Aerolysin Nanopore, Nature Nanotechnology, 11(8), 713-718.DOI: 10.1038/nnano.2016.66
17. Chan Cao†, Dong-Fang Liao†, Jie Yu, He Tian, Yi-Tao Long* (2017). Construction of an Aerolysin Nanopore in a Lipid Bilayer for Single-Oligonucleotide Analysis, Nature Protocols, 12(9), 1901-1911. (Cover) DOI: 10.1038/nprot.2017.077
18. Chan Cao, Yi-Tao Long* (2018). Biological Nanopores: Confined Spaces for Electrochemical Single-Molecule Analysis, Accounts of Chemical Research, 51(2), 331-341. DOI: 10.1021/acs.accounts.7b00143
19. Chan Cao, Meng-Yin Li, Nuria Cirauqui, Ya-Qian Wang, Matteo Dal Peraro*, He Tian, Yi-Tao Long* (2018). Mapping the Sensing Spots of Aerolysin for Single Oligonucleotides Analysis, Nature Communications, 9(1), 2823-2830. DOI: 10.1038/s41467-018-05108-5