王伟，教授、博士生导师 Wei Wang, Professor Click Here for Curriculum Vitae in English: 南京大学化学化工学院，生命分析化学国家重点实验室 国家杰青(2019)、国家优青(2015) 办公室：仙林校区化学楼D306室 联系电话Tel：025-89680309 |
Wei Wang is a Professor at Nanjing University, and a Fellow of the Royal Society of Chemistry. He received his B.S. in 2004 and Ph.D. in 2009, both from University of Science and Technology of China (USTC). He pursued postdoctoral studies at Arizona State University during 2009-2013 before joining the faculty of Nanjing University in December 2013. He received the supports from National Natural Science Foundation of China for Distinguished Young Scholars (2019). He also received the Young Chemist Award (2017) and Electrochemistry Youth Award (2021) from Chinese Chemical Society, and Particuology Youth Award from Chinese Society of Particuology in 2020. His current researches involve advanced molecular spectroscopy, optical/electrochemical sensors, and optical microscopy for studying the dynamic and heterogeneous processes at microscaled interfaces.
2004年和2009年分别从中国科学技术大学化学系获得理学学士和分析化学博士学位。2009-2013在美国亚利桑那州立大学从事博士后研究。2013年12月起任南京大学教授。2017年获得中国化学会青年化学奖。2019年获得国家自然科学基金委杰出青年科学基金资助(2020-2024)。在Nature Chemistry, PNAS, JACS, Angew. Chem. Int. Ed., Anal. Chem.等学术期刊发表研究论文80余篇。主要研究兴趣包括光学显微成像技术、纳米电化学、单颗粒化学成像与测量、单细胞和单分子分析检测等，致力于通过微纳尺度的化学成像与测量发现新的科学现象，揭示新的科学规律，不断推动对微观化学过程的认知极限。
主要学术荣誉 (Honors and Awards)
2022年，中国青年科技奖
2022年，南京大学杜厦教学奖
2021年，中国化学会电化学青年奖
2020年，第十七届江苏省青年科技奖暨“江苏省十大青年科技之星”
2020年，中国颗粒学会青年颗粒学奖
2020年，南京大学魅力导师奖
2020年，英国皇家化学会会士（FRSC）
2018年，江苏省双创团队领军人才
2017年，中国化学会青年化学奖
2015年，江苏省创新创业人才
2015年，江苏省杰出青年基金
研究领域-化学成像 (Research Interests - Chemical Imaging)
探索新的科学现象和规律离不开观察测量技术的发展。经典的化学研究往往将研究对象视为均相体系，测量结果是体系中大量个体（分子、纳米颗粒等）的系综平均行为。然而，真实的化学反应过程在时间和空间上都表现出显著的非均一性，因此亟待发展具有优异时间和空间分辨能力的化学成像技术，通过微纳尺度的成像与测量发现新的科学现象，揭示新的科学规律，不断推动对微观化学过程的认知极限。
自17世纪Robert Hooke获得第一张单细胞的光学图像以来，各种各样的光学显微镜长期被认为是生命科学而非化学科学的重要研究工具。这主要是因为光学显微镜亚微米级的分辨率适合于细胞器、细胞（细菌）和组织成像，而与化学科学研究对象的尺度相去甚远。上世纪90年代，荧光显微镜成功实现了对单个有机荧光分子和单个半导体量子点的原位成像与定量测量。随后，超分辨荧光成像、暗场散射、近场光学、拉曼散射、表面等离激元共振、光热成像等多种光学显微成像技术充分展示了其在分子科学和材料科学等化学相关领域的巨大潜力，从而翻开了基于光学显微镜的化学成像研究的新篇章。
本课题组坚持技术导向和问题导向并重的研究策略。在技术发展方面，主要着眼于以下光学成像技术的成像原理、装置搭建、性能优化、联用技术和图像数据分析等技术问题的解决和突破。主要成像技术包括： 1）表面等离激元共振显微成像（针对金属/介电物质/软物质）； 2）荧光成像（针对荧光物质）； 3）暗场散射（针对贵金属）；4）光热显微成像（针对光吸收物质）（详见Technology和Instruments页面）。在此基础上，围绕下列科学问题开展科学探索：1）显微电化学：界面电子转移过程的可视化；2）单颗粒催化：单个纳米颗粒的化学反应成像与测量；3）表面物理化学：纳米气泡和纳米液滴的行为和规律；4）单分子分析与单分子反应动力学；5）基于完整细胞的药物筛选（详见Research页面）。
欢迎对课题组研究工作感兴趣的本科生、研究生加入我们的队伍。
代表性研究论文 (Selected Publications)
21. Ben Niu, Wenxuan Jiang, Bo Jiang, Mengqi Lv, Sa Wang, Wei Wang*, Determining the depth of surface charging layer of single Prussian blue nanoparticles with pseudocapacitive behaviors, Nature Commun., 2022, 13, 2316. [URL]
20. Shasha Liu, Mengqi Lv, Haoran Li, Sa Wang, Chengdong Feng, Xiaoliang Wang, Wenbing Hu, Wei Wang*, Optical imaging of the molecular mobility of single polystyrene nanospheres, J. Am. Chem. Soc., 2022, 144, 1267-1273. [URL]
19. Shasha Liu, Kai Zhou, Tinglian Yuan, Wenrui Lei, Hong-Yuan Chen, Xin-Yi Wang, Wei Wang*, Imaging the thermal hysteresis of single spin crossover nanoparticles, J. Am. Chem. Soc., 2020, 142, 15852-15859. [URL]
18. Wei Wei, Tinglian Yuan, Wenxuan Jiang, Jia Gao, Hong-Yuan Chen, Wei Wang*, Accessing the electrochemical activity of single nanoparticles by eliminating the heterogeneous electrical contacts, J. Am. Chem. Soc., 2020, 142, 14307-14313. [URL]
17. Hua Su, Ben Niu, Haoran Li, Fei Liu, Tinglian Yuan, Hong-Yuan Chen, Wei Wang*, Evanescent Wave‐guided Growth of Organic Supramolecular Nanowire Array, Angew. Chem. Int. Ed., 2020, 59, 19209-19214. [URL]
16. Jing Chen+, Kai Zhou+, Yongjie Wang, Jia Gao, Tinglian Yuan, Jie Pang, Shu Tang, Hong-Yuan Chen, Wei Wang*, Measuring the activation energy barrier for the nucleation of single nanosized vapor bubbles, Proc. Natl. Acad. Sci. USA, 2019, 116, 12678-12683.
15. Yingyan Jiang, Hua Su, Wei Wei, Yongjie Wang, Hong-Yuan Chen, Wei Wang*, Tracking the rotation of single CdS nanorods during photocatalysis with surface plasmon resonance microscopy, Proc. Natl. Acad. Sci. USA, 2019, 116， 6630-6634.
14. Meng Li, Tinglian Yuan, Yingyan Jiang, Linlin Sun, Wei Wei, Hong-Yuan Chen, Wei Wang*, Total Internal Reflection-based Extinction Spectroscopy of Single Nanoparticles, Angew. Chem. Int. Ed., 2019, 58, 572-576.
13. Yingyan Jiang, Wei Wang*, Point Spread Function of Objective-based Surface Plasmon Resonance Microscopy, Anal. Chem., 2018, 90, 9650-9656.
12. Tao Liu, Meng Li, Yongjie Wang, Yimin Fang, Wei Wang*, Electrochemical impedance spectroscopy of single Au nanorods, Chem. Sci., 2018, 9, 4424.
11. Wei Wang*, Imaging the chemical activity of single nanoparticles with optical microscopy, Chem. Soc. Rev., 2018, 47, 2485-2508.
10. Hua Su, Yimin Fang, Fangyuan Chen, Wei Wang*, Monitoring the dynamic photocatalytic activity of single CdS nanoparticles by lighting up H2 nanobubbles with fluorescent dyes, Chem. Sci., 2018, 9, 1448-1453.
9. Yimin Fang, Zhimin Li, Yingyan Jiang, Xian Wang, Hong-Yuan Chen, Nongjian Tao, Wei Wang*, Intermittent photocatalytic activity of single CdS nanoparticles, Proc. Natl. Acad. Sci. USA, 2017, 114, 10566-10571.
8. Dan Jiang, Yingyan Jiang, Zhimin Li, Tao Liu, Xiang Wo, Yimin Fang, Nongjian Tao, Wei Wang*, Hong-Yuan Chen, Optical imaging of phase transition and Li-ion diffusion kinetics of single LiCoO2 nanoparticles during electrochemical cycling, J. Am. Chem. Soc., 2017, 139, 186-192.
7. Meisam Hasheminejad, Yimin Fang, Meng Li, Yingyan Jiang, Wei Wang*, Hong-Yuan Chen, Plasmonic Imaging of the Interfacial Potential Distribution on Bipolar Electrodes, Angew. Chem. Int. Ed., 2017, 56, 1629-1633.
6. Linlin Sun, Yimin Fang, Zhimin Li, Wei Wang*, Hong-Yuan Chen*, Simultaneous optical and electrochemical recording of single nanoparticle electrochemistry, Nano Res., 2017, 5, 1740-1748.
5. Yimin Fang, Shan Chen, Wei Wang*, Xiaonan Shan*, Nongjian Tao, Real time monitoring of phosphorylation kinetics with self-assembled nano-oscillators, Angew. Chem. Int. Ed., 2015, 54, 2538-2542.
4. Yimin Fang, Wei Wang*, Xiang Wo, Yashuang Luo, Shaowei Yin, Yixian Wang, Xiaonan Shan, Nongjian Tao*, Plasmonic Imaging of Electrochemical Oxidation of Single Nanoparticles, J. Am. Chem. Soc., 2014, 136, 12584-12587.
3. Wei Wang*, Nongjian Tao, Detection, Counting and Imaging of Single Nanoparticles, Anal. Chem., 2014, 86, 2-14.
2. Wei Wang, Yunze Yang, Shaopeng Wang, Vinay J Nagaraj, Qiang Liu, Jie Wu and Nongjian Tao*, Label-free measuring and mapping of binding kinetics of membrane proteins in single living cells, Nature Chem., 2012, 4, 846-853.
1. Wei Wang, Kyle Foley, Xiaonan Shan, Shaopeng Wang, Seron Eaton, Vinay J. Nagaraj, Peter Wiktor, Urmez Patel, Nongjian Tao*, Single cells and intracellular processes studied by a plasmonic-based electrochemical impedance microscopy, Nature Chem., 2011, 3, 249-255.
