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AddressRoom A511,  No.163, Xianlin Avenue, Qixia District, Nanjing, Jiangsu, China 
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Publications  
1、

Mn-TAT PTD-Ngb ameliorates inflammation through the elimination of damaged mitochondria and the activation of Nrf2-antioxidant signaling pathway.


Biochemical Pharmacology 2020, 178, 114055.

2、

Real-time fluorescence assays of alkaline phosphatase and ATP sulfurylase activities based on a novel PPi fluorescent probe.


Talanta 2020, 207,120311.

3、

ITRAQ-based Quantitative Proteomic Analysis of MG63 in Response to HIF-1α Inducers.


J Proteomics 2020, 211,103558.

4、

Mn-TAT PTD-Ngb attenuates oxidative injury by an enhanced ROS scavenging ability and the regulation of redox signaling pathway.


Sci. Rep. 2019, 9, 20103.

5、

Zhiyang Zhang, Jiayi Sheng, Miaomiao Zhang, Xiaoyan Ma, Zhirong Geng*, Zhilin Wang* Dual-modal imaging and excellent anticancer efficiency of cisplatin and doxorubicin loaded NaGdF4:Yb3 /Er3 nanoparticles.


RSC Adv. 2018, 8, 22216-22225.

6、

Zan Li, Jie Ding, Chunxia Chen, Jiayin Chang, Binghuan Huang, Zhirong Geng* and Zhilin Wang* Dual-target cancer theranostic for glutathione S-transferase and hypoxia-inducible factor-1a inhibition.


Chem. Commun.2017, 53, 12406-12409.

7、

Binghuan Huang, Zhirong Geng,* Shihai Yan, Zan Li, Jun Cai, and Zhilin Wang* Water-Soluble Conjugated Polymer as a Fluorescent Probe for Monitoring Adenosine Triphosphate Level Fluctuation in Cell Membranes during Cell Apoptosis and in Vivo


Anal. Chem. 2017, 89, 8816-8821.

8、

Zan Li, Shihai Yan, Chen Chen, Zhirong Geng*, Jiayin Chang, Chunxia Chen, Binghuan Huang, Zhilin Wang* Molecular visualizing and quantifying immune-associated peroxynitrite fluxes in phagocytes and mouse inflammation model


Biosensors!@!@Bioelectronics 2017, 90, 75-82.

9、

Zhirong Geng,Xiaoli Song,Zhi Xing,Jinlong Geng,Sichun Zhang,Xinrong Zhang,Zhilin Wang* Effects of selenium on the structure and function of recombinant human S-adenosyl-L-methionine dependent arsenic ( 3 oxidation state) methyltransferase in E. coli.


J. Biol. Inorg. Chem. 2009, 14, 485-496.

10、

Xiaoli Song, Zhirong Geng, Jingshu Zhu, Chengying Li, Xin Hu, Ningsheng Bian, Xinrong Zhang, ZhilinWang∗ Structure-function roles of four cysteine residues in the human arsenic ( 3 oxidation state) methyltransferase (hAS3MT) by site-directed mutagenesis.


Chem-Biol. Interact. 2009,179, 321-328.

11、

Zhiming Chen, Zhirong Geng, Dalin Shao, Yuhua Mei, Zhilin Wang* Single-Crystalline EuF3 Hollow Hexagonal Microdisks: Synthesis and Application as a Background-Free Matrix for MALDI-TOF-MS Analysis of Small Molecules and Polyethylene Glycols.


Anal. Chem. 2009, 81, 7625-7631.

12、

Zhiming Chen, Zhirong Geng, Menglu Shi, Zhihui Liu, Zhilin Wang* Construction of EuF3 hollow sub-microspheres and single-crystal hexagonal microdiscs via Ostwald ripening and oriented attachment.


CrystEngComm 2009, 11, 1591-1596./t

13、

Xianwen Kan, Zhirong Geng, Yao Zhao, Zhilin Wang*, Jun-Jie Zhu Magnetic molecularly imprinted polymer for aspirin recognition and controlled release.


Nanotechnology 2009, 20(165601).

14、

Xianwen Kan, Zhirong Geng, Zhilin Wang*, Junjie Zhu Core-Shell Molecularly Imprinted Polymer Nanospheres for the Recognition and Determination of Hydroquinone.


J. Nanosci. Nanotechno. 2009, 9, 2008-2013.

15、

Xiaoli Song, Zhirong Geng, Xiangli Li, Xin Hu, Ningsheng Bian, Xinrong Zhang, Zhilin Wang* New insights into the mechanism of arsenite methylation with the recombinant human arsenic ( 3) methyltransferase (hAS3MT).


Biochimie 2010, 92, 1397-1406.

16、

Xiaoli Song, Zhirong Geng, Chengying Li, Xin Hu, Zhilin Wang* Transition metal ions and selenite modulate the methylation of arsenite by the recombinant human arsenic ( 3 oxidation state) methyltransferase (hAS3MT).


J. Inorg. Biochem. 2010, 104, 541-550.

17、

Zhiming Chen, Zhirong Geng, Zhiyang Zhang, Zhihui Liu, Zhilin Wang* Template-free synthesis of single-crystalline SmF3 rattle-structured sub-micropumpkins.


CrystEngComm 2010, 12, 2841-2846.

18、

Xianwen Kan, Qun Zhao, Dalin Shao, Zhirong Geng, Zhilin Wang*, Jun-Jie Zhu Preparation and Recognition Properties of Bovine Hemoglobin Magnetic Molecularly Imprinted Polymers.


J. Phys. Chem. B 2010, 114, 3999-4004.

19、

Kuaibing Wang, Zhirong Geng, Yuxin Yin, Xiaoyan Ma, Zhilin Wang* Morphology effect on the luminescent property and antibacterial activity of coordination polymer particles with identical crystal structures.


CrystEngComm 2011, 13, 5100-5104.

20、

Kuaibing Wang, Yuxin Yin, Chengying Li, Zhirong Geng, Zhilin Wang* Facile synthesis of zinc(II)-carboxylate coordination polymer particles and their luminescent, biocompatible and antibacterial properties.


CrystEngComm 2011, 13, 6231-6236.

21、

Zhirong Geng, Jingshu Zhu, Jing Cao, Jinlong Geng, Xiaoli Song, Zhong Zhang, Ningsheng Bian, Zhilin Wang* Effects of polynitrogen compounds on the activity of recombinant human HIF-1αprolyl hydroxylase 3 in E. coli.


J. Inorg. Biochem. 2011, 105, 391-399.

22、

Xiaoli Song, Zhirong Geng, Xiangli Li, Qun Zhaoa, Xin Hu, Xinrong Zhang, Zhilin Wang* Functional and structural evaluation of cysteine residues in the human arsenic (t3 oxidation state) methyltransferase (hAS3MT).


Biochimie 2011, 93, 369-375.

23、

Jinghan Wen, Zhirong Geng, Yuxin Yin, Zhilin Wang* A versatile water soluble fluorescent probe for ratiometric sensing of Hg2 and bovine serum albumin.


Dalton Trans. 2011, 40, 9737-9745

24、

Jinghan Wen, Zhirong Geng, Yuxin Yin, Zhong Zhang, Zhilin Wang* A Zn2 -specific turn-on fluorescent probe for ratiometric sensing of pyrophosphate in both water and blood serum.


Dalton Trans. 2011, 40, 1984-1989. (Cover paper)

25、

Jing-Han Wen, Cheng-Ying Li, Zhi-Rong Geng, Xiao-Yan Ma, Zhi-Lin Wang* A potent antitumor Zn2 tetraazamacrocycle complex targeting DNA: the fluorescent recognition, interaction and apoptosis studies.


Chem. Commun. 2011, 47, 11330-11332.

26、

Jinghan Wen, Zhirong Geng, Yuxin Yin, Zhilin Wang* A mononuclear Mn2 complex based on a novel tris-(ethyl acetate) pendant-armed tetraazamacrocycle: Effect of pyridine on self-assembly and weak interactions.


Inorg. Chem. Commun. 2012, 21, 16-20.

27、

Yuxin Yin, Jinghan Wen, Zhirong Geng, Yizhi Li, Zhilin Wang* Two heptadentate Co(III) and Mn(III) complexes with partially deprotonated cyclen derivative bearing four hydroxypropyl pendants: structure, DNA binding and DNA cleavage.


Appl. Organometal. Chem. 2012, 26, 671-680.

28、

Kuaibing Wang, Zhirong Geng, Mingbo Zheng, Luyao Ma, Xiaoyan Ma, and Zhilin Wang* Controllable Fabrication of Coordination Polymer Particles (CPPs): A Bridge between Versatile Organic Building Blocks and Porous Copper-Based Inorganic Materials.


Cryst. Growth Des. 2012, 12, 5606-5614.

29、

Zhiming Chen, Qun Zhao, Guojin Feng, Zhirong Geng and Zhilin Wang* Self-assembled hollow rare earth fluoride alloyed architectures with controlled crystal phase and morphology.


CrystEngComm 2012, 14, 7764-7770.

30、

Shuping Wang, Xiangli Li, Xiaoli Song, Zhirong Geng, Xin Hu, and Zhilin Wang* Rapid-equilibrium kinetic analysis of arsenite methylation catalyzed by recombinant human arsenic ( 3 oxidation state) methyltransferase (hAS3MT).


J. Biol. Chem. 2012, 287, 38790-38799.

31、

Jing Cao, Zhirong Geng, Xiaoyan Ma, Jinghan Wen, Yuxin Yin and Zhilin Wang* Evidence for inhibition of HIF-1α prolyl hydroxylase 3 activity by four biologically active tetraazamacrocycles.


Org. Biomol. Chem. 2012, 10, 3913-3923.

32、

Zhiming Chen, Zhirong Geng, Dalin Shao, Zhiping Zhou and Zhilin Wang* Template-free synthesis of mesoporous NaTbF4 and NaTbF4: Eu nano-rice and their luminescence properties.


CrystEngComm 2012, 14, 2251-2257.

33、

Kuaibing Wang, Xiaoyan Ma, Dalin Shao, Zhirong Geng, Zhiyang Zhang, and Zhilin Wang*Coordination-Induced Assembly of Coordination Polymer Submicrospheres: Promising Antibacterial and in Vitro Anticancer Activities.


Cryst. Growth Des. 2012, 12, 3786-3791.

34、

Xiangli Li, Zhirong Geng*, Jiayin Chang, Shuping Wang, Xiaoli Song, Xin Hu, Zhilin Wang* Identification of the third binding site of arsenic in human arsenic (III) methyltransferase


PLoS ONE 2013, 8(12): e84231.

35、

Xiangli Li, Jing Cao, Shuping Wang, Zhirong Geng*, Xiaoli Song, Xin Hu, Zhilin Wang* Residues in Human Arsenic ( 3 Oxidation State) Methyltransferase Forming Potential Hydrogen Bond Network around S-adenosylmethionine.


PLoS ONE 2013, 8(10): e76709.

36、

Xiangli Li, Zhirong Geng*, Shuping Wang, Xiaoli Song, Xin Hu, Zhilin Wang* Functional evaluation of Asp76, 84, 102 and 150 in human arsenic(III) methyltransferase (hAS3MT) interacting with S-adenosylmethionine.


FEBS Lett. 2013, 587, 2232-2240.

37、

Jing Cao, Xiaoyan Ma, Xiaoxin Wang, Xiaobo Wang, Zhong Zhang, Zhirong Geng*, Zhilin Wang* Azole Derivatives as Novel Non-iron-chelating inhibitors of Prolyl Hydroxylase 3 for HIF-1 activation.


MedChemComm 2013, 4, 1222-1230. (Cover paper)

38、

Xiaobo Wang, Xiaoyan Ma, Zhen Yang, Zhong Zhang, Jinghan Wen, Zhirong Geng*, Zhilin Wang* An NBD-armed tetraaza macrocyclic lysosomal-targeted fluorescent probe for imaging copper(Ⅱ) ion.


Chem. Commun. 2013, 49, 11263-11265.

39、

Zhong Zhang, Lizhen Wu, Zhirong Geng, Zhilin Wang* Cadmium(II) mediated addition of methanol to nitrile-functionalized 1,4,7-triazacyclononanes.


Inorganica Chimica Acta 2014, 415, 14-21.

40、

Shuping Wang, Zhirong Geng*, Nan Shi, Xiangli Li, Zhilin Wang* The functions of crucial cysteine residues in the arsenite methylation catalyzed by recombinant human arsenic (III) methyltransferase.


PLoS ONE 2014, 9(10): e110924.

41、

Shuping Wang, Nan Shi, Zhirong Geng, Xiangli Li, Xin Hu, Zhilin Wang* Inhibitory mechanism of dimercaptopropanesulfonic acid (DMPS) in the cellular biomethylation of arsenic.


Biochimie 2014, 106, 167-174.

42、

Xiangli Li, Zhirong Geng*, Jiayin Chang, Xiaoli Song, Zhilin Wang* Mutational analysis of residues in human arsenic (III) methyltransferase (hAS3MT) belonging to 5 Å around S-adenosylmethionine (SAM).


Biochimie 2014, 107, 396-405.

43、

Xiaoyan Ma, Yuxin Yin, Zhirong Geng,* Zhen Yang, Jinghan Wen and Zhilin Wang* The first example of a model compound of RNase U2 and its intermediate with CPP directly monitored by ESI-MS.


RSC Adv. 2014, 4, 50070-50073.

44、

Xiaoyan Ma, Xiaoxin Wang, Jing Cao, Zhirong Geng*, Zhilin Wang* Effect of Proline Analogues on Activity of Human Prolyl Hydroxylase and the Regulation of HIF Signal Transduction Pathway.


PLoS ONE 2014, 9(4): e95692.

45、

Zhiyang Zhang, Xiaoyan Ma, Zhiming Chen, Kuaibing Wang, Yidan Wang, Zhirong Geng*, Zhilin Wang* Controllable synthesis of NH4Eu3F10 nanospheres and application in bioimaging.


CrystEngComm 2014, 16(7), 1296-1303.

46、

Xiaobo Wang, Zhiyang Zhang, Xiaoyan Ma, Jinghan Wen, ZhirongGeng*, Zhilin Wang* Real-time fluorescence assays of alkaline phosphatase and ATP sulfurylase activities based on a novel PPi fluorescent probe.


Talanta 2015, 137, 156–160.

47、

Zhiyang Zhang, Xiaoyan Ma, Zhirong Geng*, Kuaibing Wang and Zhilin Wang* One-step synthesis of carboxyl-functionalized rare-earth fluoride nanoparticles for cell imaging and drug delivery.


RSC Adv., 2015, 5, 33999-34007.

48、

Zan Li, Zhirong Geng*, Cui Zhang, XiaoboWang, ZhilinWang* BODIPY-based azamacrocyclic ensemble for selective fluorescence detection and quantification of homocysteine in biological applications.


Biosensors and Bioelectronics 2015, 72, 1–9.

49、

Shuping Wang, Min Zhou, Jian Ouyang, Zhirong Geng*, Zhilin Wang* Tetraarsenictetrasulfide and arsenic trioxide exert synergistic effects on induction of apoptosis and differentiation in acute promyelocytic leukemia cells.


PLoS ONE 2015, 10(6): e0130343.

50、

Shuping Wang, Zhirong Geng*, Nan Shi, Xiangli Li, Zhilin Wang* Dose-dependent effects of selenite (Se4 ) on arsenite (As3 )-induced apoptosis and differentiation in acute promyelocytic leukemia cells.


Cell death!@!@Dis 2015, 6, e1596.

51、

Xianwen Kan, Yao Zhao, Zhirong Geng, Zhilin Wang*, Jun-Jie Zhu Composites of Multiwalled Carbon Nanotubes and Molecularly Imprinted Polymers for Dopamine Recognition.


J. Phys. Chem. C 2008, 112, 4849-4854.

52、

Xianwen Kan, Qun Zhao, Zhong Zhang, Zhilin Wang*, Jun-Jie Zhu Molecularly imprinted polymers microsphere prepared by precipitation polymerization for hydroquinone recognition.


Talanta 2008, 75, 22-26

53、

Chunxia Chen, Jing Cao, Xiaoyan Ma, Xiaobo Wang, Qiuyun Chen, Shihai Yan, Ningwei Zhao*, Zhirong Geng* Zhilin Wang* Neuroprotection by Polynitrogen Manganese Complexes: Regulation of Reactive Oxygen Species- Related Pathways.


Scientific Reports 2016, 6, 20853.

54、

Bing-Huan Huang, Zhi-Rong Geng*, Xiao-Yan Ma, Cui Zhang, Zhi-Yang Zhang, Zhi-Lin Wang* Lysosomal ATP imaging in living cells by a water-soluble cationic polythiophene derivative.


Biosensors and Bioelectronics 2016, 83, 213–220.