(57) Jie Sheng, Xu Cheng*

Electrochemical mono-Deuterodefluorination of Trifluoromethyl Aromatic Compounds with Deuterium Oxide

CCS Chem. Accepted. DOI:  https://doi.org/10.31635/ccschem.023.202302835

(56) Xiaofeng Zhang, Xu Cheng*

Electrochemical Reductive Functionalization of Alkenes with Deuterochloroform as a One-Carbon Deuteration Block
Org. Lett.2022, 24, 8645-8650

(55) Weijie Ding, Mengfan Li, Jinkun Fan, Xu Cheng*

Palladium-catalyzed asymmetric allylic 4-pyridinylation via electroreductive substitution reaction

Nat. Commun.2022, 13, 5642.

This work is selected as one contribution to Editors' Highlights aiming to showcase the 50 best papers recently published in Organic chemistry and chemical biology.

(54) Lei Zhang, Xu Cheng*b, Qi-Lin Zhou*a

Electrochemical Synthesis of Sulfonyl Fluorides with Triethyla-mine Hydrofluoride

Chin. J. Chem. 2022, 40, 1687-1692

(53) Weijie Dinga#, Jie Shenga#, Jin Li*b, Xu Cheng*a

Electroreductive 4‑Pyridylation of Unsaturated Compounds Using Gaseous Ammonia as Hydrogen Source

Org. Chem. Front. 2022, 9, 2634-2639.

(52) Shuai Liu, Xu Cheng*

Insertion of ammonia into alkenes to build aromatic N-heterocycles

Nat. Commun.2022, 13, 425

(51) Xu Cheng*a, Aiwen Lei*b, Tiansheng Mei*c, Hai-Chao Xu*d, Kun Xu*e, Chengchu Zeng*e

Recent Applications of Homogeneous Catalysis in Electrochemical Organic Synthesis

CCS Chem. 2022, 4, 1120-1152

(50) Recent advances in organic electrosynthesis employing transition metal complexes as electrocatalysts

Cong Maa, Ping Fanga, Zhao-Ran Liua, Shi-Shuo Xua, Kun, Xub*, Xu Chengc*, Aiwen Leid*, Hai-Chao Xue*, Chengchu, Zengb*, Tian-Sheng Meia

Science Bulletin, 2021, 66, 2412-2429


(49) 芳基碘介导的缺电子烯烃电化学氮杂环丙烷化反应 

刘峰, 戴洁,*, 程旭,*    

Aryl-Iodide-Mediated Electrochemical Aziridination of Electron-Deficient Alkenes 

Feng Liu, Jie Dai,*, Xu Cheng* 

Chin. J. Org. Chem. DOI: 10.6023/cjoc202105046

Contribution to the Special Issue: 100th Anniversary of College of Chemistry Nankai University

(48) Electrochemical Tandem Olefination and Hydrogenation Reaction with Ammonia

Xiaofeng Zhang, Runze Jiang, and Xu Cheng*

J. Org. Chem.2021, DOI: 10.1021/acs.joc.1c01024

For Special Issue “Electrochemistry in Synthetic Organic Chemistry”

(47) Ring-Contraction of Hantzsch Ester and Derivatives to Pyrrole via Electrochemical Extrusion of Ethyl Acetate out of Aromatic Rings

Xu Liu, Chang Liu, Xu Cheng*

Green Chemistry, 2021233468-3473

(46) Chlorination Reaction of Aromatic Compounds and Unsaturated Carbon-Carbon Bonds with Chlorine on Demand

Feng Liu, Na Wu, Xu Cheng*

Org. Lett., 202123, 3015-3020

(45) Electrochemical Aziridination of Tetrasubstituted Alkenes with Ammonia

Shuai Liu, Wenxuan Zhao, Jin Li1, Na Wu, Chang Liu, Xin Wang, Shuohao Li, Yan Zhu, Yong Liang*, Xu Cheng*

CCS Chemistry, 2021, DOI: 10.31635/ccschem.021.202100826

(44Electrochemical Reduction of Nitroarenes with Gaseous Ammonia 

Chang Liu, † Jin Li, † Na Wu, and Xu Cheng*

Org. Biomol. Chem., 2021, 19, 2468 - 2472

(43) Electrochemical Allylic Hydrodefluorinative Reaction using Gaseous Ammonia

Sheng Jie; Wu Na; Liu Xu; Liu Feng; Liu Shuai; Ding Weijie; Liu Chang; Cheng Xu

Chin. J. Org. Chem.2020, 40, 3873-3880


(42) Chemical‐Reductant‐Free Electrochemical Deuteration Reaction using Deuterium Oxide

Xu Liu, Ruoyu Liu, Jiaxing Qiu, Xu Cheng*, Guigen Li

Angew. Chem. Int. Ed. Accepted.



(41) Experimenting with a Suzuki–Miyaura Cross-Coupling Reaction That Demonstrates Tolerance toward Aldehyde Groups To Teach Undergraduate Students the Fundamentals of Transition-Metal-Catalyzed Reactions

Jie Dai, Dadong Lu, Tao Ye, Shouyun Yu*, Xu Cheng*

J. Chem. Edu.2019, 96, 2672-2675



(40) Electrochemical Approach for Direct C−H Phosphonylation of Unprotected Secondary Amine

Min Huang, Jie Dai, Xu Cheng,* and Mengning Ding*

Org. Lett., 2019, 21, 7759-7762



(39) An Electrochemical Cinnamyl C-H Amination Reaction Using Carbonyl Sulfamate

Shuai Liu, Jin Li, Dalin Wang, Feng Liu, Xu Liu, Yongyuan Gao, Jie Dai, Xu Cheng*

Chin. J. Chem. 2019,37, 570—574


(38) Electrochemical hydrogenation with gaseous ammonia

Jin Li, Linfeng He, Xu Liu, Xu Cheng*, Guigen Li

Angew. Chem. Int. Ed. 2019, 58, 1759-1763



(37) Application of Hantzsch Ester and Meyer Nitrile in Radical Alkynylation Reactions

Xu Liu, Ruoyu Liu, Jie Dai, Xu Cheng*, and Guigen Li

Org. Lett. 2018, 20, 6906-6909

This work is highlighted by www.organic-chemistry.org!


(36) Electrochemical Aziridination via Alkene Activation with a Sulfamate as Nitrogen Source

Jin Li, Wenhao Huang, Jingzhi Chen, Lingfeng He, Xu Cheng*, Guigen Li

Angew. Chem. Int. Ed. 2018, 57, 5695-5698.


(35) Organocatalytic reductive coupling of aldehydes with 1,1-diarylethylenes using an in situ generated pyridine-boryl radical

Jia Cao, Guoqiang Wang, Liuzhou Gao, Xu Cheng and Shuhua Li*

Chem. Sci.2018, 9, 3664-3671




(34) Visible-Light-Induced Difluoropropargylation Reaction with Benzothiazoline as a Reductant

Jingzhi Chen, Wenhao Huang, Ying Li, Xu Cheng*

Adv. Synth. Catal., 2018, 360, 1466-1472.



(33) E-Z Isomerization of 1,5-Bromotrichloromethylation Reaction Products and Trisubstituted Styrenes

Jin Li, Jingzhi Chen, Wenhao Huang,Xu Cheng*

Chin. J. Org. Chem.,2018, 38(6) : 1507-1515



(32) Photoredox C–F Quaternary Annulation Catalyzed by a Strongly Reducing Iridium Species

Peng Dai, Junyu Ma, Wenhao Huang, Wenxin Chen, Na Wu, Shengfu Wu, Ying Li, Xu Cheng*, Renxiang Tan*

ACS Catal., 2018, 8, 802–806



(31) Hydrophosphonodifluoromethylation of Alkenes via Thiyl-Radical/Photoredox Catalysis

Wenhao Huang, Jingzhi Chen, Daocheng Hong, Wenxin Chen, Xu Cheng,* Yuxi Tian,* and Guigen Li

J. Org. Chem., 2018, 83, 578–587




(30) Substituted Hantzsch Esters as Versatile Radical Reservoirs in Photoredox Reactions

Fangjun Gu, Wenhao Huang, Xu Liu, Wenxin Chen, Xu Cheng*

Adv. Synth. Catal.2018, 360, 925-931


(29) Guoqiang Wang,a Jia Cao,a,cLiuzhou Gao,a Wenxin Chen,b Wenhao Huang,b XuCheng,b,d* and Shuhua Lia*

Metal-Free Synthesis of C-4 SubstitutedPyridine Derivatives Using Pyridine-boryl Radicals via a RadicalAddition/Coupling Mechanism: A Combined Computational and Experimental Study

J. Am. Chem. Soc. 2017, 139, 3904-3910 .


(28) Wenhao Huang, Xu Cheng*

Hantzsch esters as multifunctional reagentsin visible-light photoredox catalysis

Synlett, 2017, 28, 148-158, Invited Synpact.


(27) Wenhao Huang, Wenxin Chen, Guoqiang Wang, Jin Li,Xu Cheng,* and Guigen Li
Thiyl-Radical-Catalyzed Photoreductive Hydrodifluoroacetamidation of Alkenes with Hantzsch Ester as Multifunctional Reagent
ACS Catal., 2016, 6, 7471–7474
Highlighted by X-MOL 



(26) Jin Li, Jingzhi Chen, Wei Jiao, Guoqiang Wang, Ying Li, Xu Cheng,* Guigen Li
Difluoroalkylation/C-Hannulation cascade reaction induced by visible-light photoredox catalysis
J. Org. Chem.201681 (20), 9992–10001
Highlighted by Org. Process Res. Dev. 2016, 20, 1839.


(25) Wenxin Chena, Zheng Liua, Jiaqi Tianb, Jin Lia, Jing Mab*, Xu Chenga*, Guigen Lia,c
Building Congested Ketone: Substituted HantzschEster and Nitrile as Alkylation Reagents in Photoredox catalysis
J. Am. Chem. Soc., 2016, 138, 12312–12315.


(24) Jie Cheng, Xia Deng, Guoqiang Wang, Ying Li, Xu Cheng*,and Guigen Li
Intermolecular C–H Quaternary Alkylation ofAniline Derivatives Induced by Visible-Light Photoredox Catalysis
Org. Lett.2016, 18, 4538–4541.


(23) Wenxin Chen, Huachen Tao, Wenhao Huang, Guoqiang Wang, Shuhua Li,* Xu Cheng,* Guigen Li
Hantzsch Ester as a Photosensitizer for Visible-Light-Induced Debromination of Vicinal Dibromo Compounds
Chem. Eur. J. 2016, 22, 9546-9550.


(22) Jun Fei, Zhen Wang, Zheren Cai, HaoSun, Xu Cheng*
Synthesis of α-TertiaryAmine Derivatives by Intermolecular Hydroamination of Unfunctionalized Alkeneswith Sulfamates under

Trifluoromethanesulfonic Acid Catalysis
Adv. Synth. Catal.2015, 357, 4063357.


(21) Zheng Liu, Yi Zhang, Zheren Cai, Hao Sun, and Xu Cheng*
Photoredox Removal of p-Methoxybenzyl Ether Protecting Group withHydrogen Peroxide as Terminal Oxidant
Adv. Synth. Catal. 2015, 357, 589.


(20) Yi Zhang, Yuchi Dai, Guigen Li, Xu Cheng*
The Catalytic Synthesis of Carboniolamide:the Role of sp3 Hybridized Oxygen
Synlett2014, 25, 2644.


(19) Yi Zhang, Zhihao Zhong, Yingmei Han, Ruirui Han, Xu Cheng*
A convenientsynthesis of bisamides with BF etherate ascatalyst
Tetrahedron. 2013, 69, 11080.



Prior to NJU

(18) Arun K. Ghosh*, Xu Cheng, Bing Zhou
Enantioselective Total Synthesis of (+)-Lithospermic Acid
Org. Lett. 2012,14, 5046-5049.


(17) Arun K. Ghosh*,Xu Cheng, Ruoli, Bai, Arni Hamel
Total Synthesis of Poetent Antitumor Macrolide, (-)-Zampanolide: An Oxidative C-H Bond Activation-Based Strategy.
Eur. J. Org.Chem. 2012, 4130.



(16) Arun K. Ghosh*, Xu Cheng,
Synthesis of Functionalized 4-Methylenetetrahydropyrans by Oxidative C-H Activation of Allyl or Benzyl Ethers.
Tetrahedron Lett. 2012, 53, 2568-2570.


(15) Xu Cheng, Nicole L. Harzdorf, Zin Khaing, Danby Kang, Andrew M. Camelio, Travis Shaw, Christine E. Schmidt, and Dionicio Siegel*
Neuronal Growth Promoting Sesquiterpene-Neolignans;Syntheses and Biological Studies
Org. Biomol. Chem. 2012,10, 383.


(14) Arun K. Ghosh*,  Xu Cheng
Enantioselective Total Synthesis of (−)-Zampanolide, a Potent Microtubule-Stabilizing Agent
Org. Lett. 2011, 13, 4108. (one of most accessed papers in August). 


(13) Xu Cheng, Nicole L. Harzdorf, Travis Shaw and Dionicio Siegel*
Biomimetic Syntheses of the Neurotrophic Natural Products Caryolanemagnolol and Clovanemagnolol
Org. Lett. 2010, 12, 1304. 


(12) Xu Cheng, Sreekumar Vellalath, Richard Goddard, and Benjamin List*
Direct Catalytic Asymmetric Synthesis of Cyclic Aminals from Aldehydes
J. Am. Chem.Soc. 2008,130, 15786. 


(11) Nolwenn J. A. Martin, Xu Cheng, and Benjamin List*
Organocatalytic Asymmetric Transferhydrogenation of β-Nitroacrylates: Accessing β2-Amino Acids
J. Am. Chem. Soc. 2008, 130, 13862.


(10) Xu Cheng, Richard Goddard, Gernot Buth, Benjamin List*
Direct Catalytic Asymmetric Three-Component Kabachnik-Fields Reaction
Angew. Chem. Int. Ed. 2008, 47, 5079. 


(9) Ji-Chao Yan, Xu Cheng, Qi-Lin Zhou*, and Jian Pei*
Chiral Polyfluorene Derivatives: Synthesis, Chiroptical Properties, and Investigation of the Structure−Property Relationships
Macromolecules. 2007,40, 832. 


(8) Xu Cheng, Jian-Hua Xie, Sheng Li, Qi-Lin Zhou*
Asymmetric Hydrogenation of a,β-Unsaturated Carboxylic Acids Catalyzed by Ruthenium(II) Complexes of Spirobifluorene Diphosphine (SFDP) Ligands 
Adv. Synth. Catal.2006, 348, 1271. 


(7) Xu Cheng, Shou-Fei Zhu, Xiang-Chen Qiao, Pu-Cha Yan, Qi-Lin Zhou*
A general synthetic route to chiral dihydroxy-9,9′-spirobifluorenes
Tetrahedron.2006, 62, 8077. 


(6) Jian-Hua Xie, Sheng Liu, Xiang-Hong Huo, Xu Cheng, Hai-Feng Duan, Bao-Min Fan, Li-Xin Wang, Qi-Lin Zhou*
Ru-II-SDP-complex-catalyzed asymmetric hydrogenation of ketones. Effect of the alkali metal cation in the reaction
J. Org. Chem.2005, 70, 2967. 


(5) Xu Cheng, Qi Zhang, Jian-Hua Xie, Qi-Lin Zhou*
Highly Rigid Diphosphine Ligands with Large Dihedral Angle Based on Chiral Spirobifluorene Backbone
Angew. Chem. Int. Ed.2005, 44, 1118. 


(4) Xu Cheng, Guo-Hua Hou, Jian-Hua Xie, Qi-Lin Zhou*
Synthesis and optical resolution of 9,9'-spirobifluorene-1, 1'-diol
Org. Lett.2004, 6, 2381. 


(3) Jian-Hua Xie, Hai-Feng Duan, Bao-Min Fan, Xu Cheng, Li-Xin Wang, Qi-Lin Zhou*
Application of SDP Ligands for Pd-catalyzed allylic alkylation
Adv. Synth. Catal.2004, 346, 625.


(2) Xiao-Guang Li, Xu Cheng, Qi-Lin Zhou*
A convenient synthesis of 2-alkyl-8-quinoline carboxylic acids
Synth. Commun.2002, 32, 2477. 


(1) Xiao-Guang Li, Xu Cheng, Jun-An Ma, Qi-Lin Zhou*
Synthesis of chiral 2-alkyl-8-quinolinyl-oxazoline ligands: reversal of enantioselectivity in the asymmetric palladium-catalyzed allylic alkylation
J. Organomet. Chem. 2001, 640, 65.



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