| Publications

2019
64.

Hua Shi, Yidan Sun, Runqi Yan, Shunli Liu, Li Zhu, Song Liu, Yuzhang Feng, Peng Wang, Jian He*, Zhengyang Zhou*, and Deju Ye*. Magnetic Semiconductor Gd-Doping CuS Nanoparticles as Activatable Nanoprobes for Bimodal Imaging and Targeted Photothermal Therapy of Gastric Tumors. Nano Lett. 201919, 937–947.

63.

Muhammad Rizwan Younis, Chen Wang, Ruibing An, Shouju Wang, Muhammad Adnan Youni, Zhong-Qiu Li, Yang Wang, Ayesha Ihsan, Deju Ye, and Xing-Hua Xia*. Low Power Single Laser Activated Synergistic Cancer Phototherapy Using Photosensitizer Functionalized Dual Plasmonic Photothermal Nanoagents. ACS Nano, 2019, DOI: 10.1021/acsnano.8b09552.

62.

Yuqi Wang, Xiaoming Hu, Jianhui Weng, Jinbo Li, Quli Fan, Yan Zhang, and Deju Ye*A Photoacoustic Probe for the Imaging of Tumor Apoptosis by Caspase-Mediated Macrocyclization and Self-Assembly. Angew. Chem. Int. Ed. 2019, https://doi.org/10.1002/anie.201813748. (VIP)

2018
61.

Luyan Wu, Yidan Sun, Keisuke Sugimoto, Zhiliang Luo, Yusuke Ishigaki, Kanyi Pu, Takanori Suzuki*, Hong-Yuan Chen, and Deju Ye*Engineering of Electrochromic Materials as Activatable Probes for Molecular Imaging and Photodynamic Therapy  J. Am. Chem. Soc. 2018140, 16340-16352.

60.

Zhiliang Luo, Ruibing An, Deju Ye*. Recent Advances in the Development of Optical Imaging Probes for γ‐Glutamyltranspeptidase. ChembioChem. 2019, 10, 474-487. (Invited. https://doi.org/10.1002/cbic.201800370)

       

59.

Ruibing An, Zhanni Gu, Haifeng Sun, Yuxuan Hu, Runqi Yan, Deju Ye* and Hong Liu*. Self‐assembly of Fluorescent Dehydroberberine Enhances Mitochondria‐Dependent Antitumor Efficacy. Chem. Eur. J. 2018, 24, 9812 – 9819. (Hot Paper, Cover Picture).

  

58.

Yuqi Wang, Ruibing An, Zhiliang Luo, Deju Ye*Firefly Luciferin‐Inspired Biocompatible Chemistry for Protein Labeling and In Vivo ImagingChem. Eur. J. 201824, 5707-5722 (Invited)

57.

Zhiliang Luo, Zheng Huang, Ke Li, Yidan Sun, Jianguo Lin*, Deju Ye* and Hong-Yuan Chen. Targeted Delivery of γ-Glutamyl Transpeptidase-Activatable Near-Infrared Fluorescence Probe for Selective Cancer Imaging. Anal. Chem. 2018, 90, 2875-2883.

   

 

56.

Hua Shi, Runqi Yan, Luyan Wu, Yidan Sun, Song Liu, Zhengyang Zhou*, Jian He*, Deju Ye*. Tumor-targeting CuS nanoparticles for multimodal imaging and guided photothermal therapy of lymph node metastasis. Acta Biomaterialia, 201872, 256.

  

55.

Yue Zhang, Kewei Ren, Xiaobo Zhang, Zhicong Chao, Yuqin Yang, Deju Ye, Zhihui Dai, Ying Liu,* Huangxian Ju*  Photo-tearable tape close-wrapped upconversion nanocapsules for near-infrared modulated efficient siRNA delivery and therapy. Biomaterials 2018, 163, 55-66

54.

Tai-Bao Gao#, Jing-Jing Zhang#, Run-Qi Yan, Deng-Ke Cao*, Dechen Jiang*, and Deju Ye*.  Aggregation-Induced Electrochemiluminescence from a Cyclometalated Iridium(III) ComplexInorg. Chem. 201857, 4310-4316.

2017
53.

Liandong Feng, Yuqi Wang, Zhiliang Luo, Zheng Huang, Yan Zhang, Kai Guo,* and Deju Ye*. Dual Stimuli‐Responsive Nanoparticles for Controlled Release of Anticancer and Anti‐inflammatory Drugs Combination. Chem. Eur. J. 2017,23, 9397-9406.

 

52.

Zhiliang Luo+, Liandong Feng+, Ruibing An, Guanfu Duan, Runqi Yan, Hua Shi, Jian He, Zhengyang Zhou, Changge Ji, Hong-Yuan Chen, and Deju Ye*

Activatable Near‐Infrared Probe for Fluorescence Imaging of γ‐Glutamyl Transpeptidase in Tumor Cells and In VivoChem. Eur. J. 2017, 23, 14778-14785 (Hot Paper, Cover Picture)

51.

Yizhong Shen, Nan Zhang, Yidan Sun, Wei-Wei Zhao, Deju Ye*, Jing-Juan Xu, and Hong-Yuan Chen*. Activatable QD-Based Near-Infrared Fluorescence Probe for Sensitive Detection and Imaging of DNA. ACS Appl. Mater. Interfaces 2017, 9, 25107−25113.

50.

Shan-Shan Li, Qi-Yuan Guan, Mengmeng Zheng, Yuqi Wang, Deju Ye, Bin Kang, Jing-Juan Xu, Hong-Yuan Chen. Simultaneously quantify multiple endogenous biothiols in single living cells by plasmonic Raman probes. Chem. Sci. 2017, 8, 7582-7587.

49.

Yizhong Shen, Yidan Sun, Runqi Yan, Erquan Chen, Huan Wang, Deju Ye*, Jing-Juan Xu*, Hong-Yuan Chen*. Rational engineering of semiconductor QDs enabling remarkable 1 O 2 production for tumor-targeted photodynamic therapy. Biomaterials. 2017, 148, 31-40.

48.

Tai-Bao Gao, Run-Qi Yan, Alexander J. Metherell, Deng-Ke Cao*, Deju Ye* and Michael D. Ward*cd.Coordination mode-induced isomeric cyclometalated [Ir (tpy)(nbi) Cl](PF6) complexes: distinct luminescence, self-assembly and cellular imaging behaviors. Dalton Trans., 2017, 46, 16787-16791.

47.

Yizhong Shen, Qian Tian, Yidan Sun, Jing-Juan Xu, Deju Ye*, and Hong-Yuan Chen*. ATP-Activatable Photosensitizer Enables Dual Fluorescence Imaging and Targeted Photodynamic Therapy of Tumor. Anal. Chem. 2017, 89, 13610-13617.

2016
46.

Yu ZhouJun LiuMingyue ZhengShuli ZhengChunyi JiangXiaomei ZhouDong ZhangJihui ZhaoDeju YeMingfang ZhengHualiang JiangDongxiang LiuJian ChengHong Liu. Structural optimization and biological evaluation of 1,5-disubstituted pyrazole-3-carboxamines as potent inhibitors of human 5-lipoxygenase. Acta Pharm. Sin. B 2016, 6, 32-45.

45.

Runqi Yan, Deju Ye*. Molecular imaging of enzyme activity in vivo using activatable probes. Sci. Bull. 2016, 61, 1672-1679

44.

Yizhong Shen, Adam Shuhendler, Deju Ye*, Jing-Juan Xu, Hong-Yuan Chen*. Two-photon excitation nanoparticles for photodynamic therapy. Chem. Soc. Rev. 2016, 45, 6725-6741 (inside cover)

43.

Mengmeng Zheng, Yuqi Wang, Hua Shi, Yuxuan Hu, Liandong Feng, Zhiliang Luo, Mi Zhou, Jian He, Zhenyang Zhou*, Yan Zhang*, and Deju Ye*. Redox-mediated disassembly to build activatable trimodal probe for molecular imaging of biothiols. ACS Nano 2016, 10, 10075-10085.

 

42.

Yuqi Wang, Jinbo Li, Liandong Feng, Jingfang Yu, Yan Zhang,* Deju Ye*, and Hong-Yuan Chen. Lysosome-targeting fluorogenic probe for cathepsin B imaging in living cells. Anal. Chem. 2016, 88, 12403-12410.

2015
41.

Mengmeng Zheng, Haixiao Huang, Mi Zhou, Yuqi Wang, Yan Zhang*, Deju Ye*, Hong-Yuan Chen. Cysteine-mediated intracellular building of luciferin to enhance probe retention and fluorescence turn-on (* Corresponding authors). Chem. Eur. J. 2015, 21, 10506-10512.

40.

Hossein Nejadnik#, Deju Ye#, Olga, Lenkov, John Martin, Jessica Doing, Rostislav Castillo, Nikita Derugin, Barbara Sennino, Jianghong Rao, Heike Daldrup-Link. MR imaging of stem cell apoptosis in arthritic joints with a caspase-activatable contrast agent (# Co-first author). ACS Nano. 2015, 9, 1150-1160.

39.

Adam J. Shuhendler#, Deju Ye#, Kimberly D. Brewer#, Magdalena Bazalova-Carter, Kyung-Hyun Lee, Paul Kempen, K. Dane Wittrup, Edward E. Graves, Brian Rutt , Jianghong Rao (# Co-first authors).  Molecular Magnetic Resonance Imaging of Tumor Response to Therapy.  Sci. Rep. 2015, 5, 14759.

38.

Xu Zhang, Qian Ba, Zhanni Gu, Diliang Guo, Yu Zhou, Yungen Xu, Hui Wang*, Deju Ye*, Hong Liu*. Fluorescent Coumarin-Artemisinin Conjugates as Mitochondria-Targeting Theranostic Probes for Enhanced Anticancer Activities (* Corresponding authors). Chem. Eur. J. 2015, 21, 17415-17421.

2014
37.

Deju Ye, Prachi Pandit, Paul Kempen, Jianguo Lin, Liqing Xiong, Robert Sinclair, Brian Rutt, and Jianghong Rao. Redox-triggered self-Assembly of gadolinium-based MRI probes for sensing reducing environment. Bioconjugate Chem. 2014, 25, 1526-1536. (ACS Editor Choice’s Article on Jul-21, 2014)

36.

Deju Ye#, Adam J. Shuhendler#, Prachi Pandit#, Kimberly D. Brewer, Brian Rutt, and Jianghong Rao. Caspase-responsive smart gadolinium-based contrast agent for magnetic resonance imaging of drug-induced apoptosis. Chem. Sci. 2014, 5, 3845-3852. (# Co-first author)

35.

Deju Ye#, Adam J. Shuhendler#, Lina Cui, Ling Tong, Sui Seng Tee, Grigory Tikhomirov, Dean W. Felsher and Jianghong Rao. Bioorthogonal Cyclization-mediated In Situ self-assembly of small-molecule probes for imaging caspase activity in living mice. Nature Chem. 2014, 6, 519-526. (# Co-first author)

2013
34.

Enguang FengWoo-Jin ShinXuelian ZhuJian LiDeju YeJiang WangMingyue ZhengJian-Ping ZuoKyoung Tai NoXian LiuWeiliang Zhu,Wei TangBaik-Lin SeongHualiang Jiang, and Hong Liu. Structure-Based Design and Synthesis of C-1- and C-4-Modified Analogs of Zanamivir as Neuraminidase Inhibitors. J. Med. Chem. 2013, 56, 671-684.

33.

Bin Shen, Jongho Jeon, Mikael Palner, Deju Ye, Adam Shuhendler, Frederick T. Chin, and Jianghong Rao. Positron Emission Tomography Imaging of Drug-Induced Tumor Apoptosis with a Caspase-Triggered Nano-aggregation Probe. Angew. Chem. Int. Ed. 2013, 52, 10511-10514 (Inside cover paper).

2012
32.

Enguang, Feng, Deju Ye, Jian Li, Dengyou Zhang, Jinfang Wang, Fei Zhao, Rolf Hilgenfeld, Mingyue Zheng, Hualiang Jiang, and Hong Liu. Recent Advances in Neuraminidase inhibitor Development as Anti-influenza Drugs. ChemMedChem 2012, 7, 1527-1536.

31.

Deju Ye#, Woo-Jin Shin#, Ning Li#, Wei Tang, Enguang Feng, Jian Li, Pei-Lan He, Jian-Ping Zuo, Hanjo Kim, Ky-Youb Nam, Weiliang Zhu, Baik-Lin Seong, Kyoung Tai No, Hualiang Jiang, and Hong Liu. Synthesis of C-4 Modified Zanamivir Analogs as Neuraminidase Inhibitors and Their Anti-AIV activities. Eur. J. Med. Chem. 2012, 54, 764-770. (# Co-first author)

2011
30.

Dengyou Zhang, Deju Ye, Enguang Feng, Jinfang Wang, Jianmei Shi, Hualiang Jiang, and Hong Liu. Highly alpha-Selective Synthesis of Sialyl Spirohydantoins by Regiospecific Domino Condensation/O®N Acyl Migration/N-Sialylation of Carbodiimides with Peracetylated Sialic Acid. J. Org. Chem. 2010, 75, 3552–3557.

29.

Lei Zhang, Deju Ye, Yu Zhou, Guannan Liu, Enguang Feng, Hualiang Jiang, and Hong Liu. Regioselective Synthesis of 3-Benzazepinones and Unexpected 5-Bromo-3-benzazepinones. J. Org. Chem. 2010, 75, 3671–3677.

28.

Xu Zhang, Yu Zhou, Hengshuai Wang, Diliang Guo, Deju Ye, Yungen Xu, Hualiang, Jiang, and Hong Liu. Silver-catalyzed intramolecular hydroamination of alkynes in aqueous media: efficient and regioselective synthesis for fused benzimidazoles. Green Chem. 2011, 13, 397–405.

27.

Deju Ye, Jinfang Wang, Dengyou Deng, Enguang Feng, Hualiang Jiang, and Hong Liu. Advances in O-Sialylation. Progress in Chemistry 2010, 22, 91–100.

26.

Xu Zhang, Yu Zhou, Hengshuai Wang, Diliang Guo, Deju Ye, Yungen Xu, Hualiang, Jiang, and Hong Liu. An Effective Synthetic Entry to Fused Benzimidazoles via Iodocyclization. Adv. Synth. Catal. 2011, 353, 1429–1437.

25.

Diliang Guo, Tao Chen, Deju Ye, Jinyi Xu, Hualiang Jiang, Kaixian Chen, Hui Wang, and Hong Liu. Cell-Permeable Iminocoumarine-Based Fluorescent Dyes for Mitochondria. Org. Lett. 2011, 13, 2884–2887.

24.

Deju Ye, Gaolin Liang, Man Lung Ma, and Jianghong Rao. Controlling Intracellular Macrocyclization for the Imaging of Protease Activity. Angew. Chem. Int. Ed. 2011, 50, 2275–2279.

23.

Gaolin Liang, John Ronald, Yuanxin Chen, Deju Ye, Prachi Pandit, Man Lung Ma, Brian Rutt, and Jianghong Rao. Controlled Self-Assembling of Gadolinium Nanoparticles as Smart Molecular Magnetic Resonance Imaging Contrast Agents. Angew. Chem. Int. Ed. 2011, 50, 6283–6286.

22.

Yu Zhou, Yun Zhai, Xun Ji, Guannan Liu, Enguang Feng, Deju Ye, Linxiang Zhao, Hualiang Jiang, and Hong Liu. Gold(I)-Catalyzed One-Pot Tandem Coupling/Cyclization: An Efficient Synthesis of Pyrrolo-/Pyrido[2,1-b]benzo[d][1,3]oxazin-1-ones. Adv. Synth. Catal. 2010, 352, 373–378.

2010
21.

Yu Zhou, Yun Zhai, Jian Li, Deju Ye, Hualiang Jiang, and Hong Liu. Metal-free tandem reaction in water: An efficient and regioselective synthesis of 3-hydroxyisoindolin-1-ones. Green Chem. 2010, 12, 1397–1404.

20.

Haifeng Sun, Deju Ye, Hualiang Jiang, Kaixian Chen, and Hong Liu. One-Pot Approach for C-C Bond Formation through Ruthenium-Amido Complex Catalyzed Tandem Aldol Reaction/Hydrogenation. Synthesis 2010, 15, 2577–2582.

19.

Enguang Feng, He Huang, Yu Zhou, Deju Ye, Hualiang Jiang, and Hong Liu. Metal-Free Synthesis of 2-Substituted (N, O, C) Benzothiazoles via an Intramolecular C-S Bond Formation. J. Comb. Chem. 2010, 12, 422–429.

18.

Deju Ye#, Yu Zhang#, Fei Wang#, Mingfang Zheng, Xu Zhang, Xiaoming Luo, Xu Shen, Hualiang Jiang, and Hong Liu. Novel thiophene derivatives as PTP1B inhibitors with selectivity and cellular activity. Bioorg. Med. Chem. 2010, 18, 1773–1782. (# Co-first author)

2009
17.

Xiaodong Zhang, Deju Ye, Haifeng Sun, Diliang Guo, Jiang Wang, He Huang, Xu Zhang, Hualiang Jiang, and Hong Liu. Microwave-assisted synthesis of quinazolinone derivatives by efficient and rapid iron-catalyzed cyclization in water. Green Chem. 2009, 11, 1881–1888.

16.

Jian Li, Deju Ye, Hong Liu, Xiaomin Luo, and Hualiang Jiang. Microwave-assisted dehalogenation of a-haloketones by zinc and ammonium chloride in alcohol. Synth. Commun. 2008, 38, 567–575.

15.

Enguang Feng, He Huang, Yu Zhou, Deju Ye, Hualiang Jiang, and Hong Liu. Copper(I)-Catalyzed One-Pot Synthesis of 2H-1,4-Benzoxazin-3-(4H)-ones from o-Halophenols and 2-Chloroacetamides. J. Org. Chem. 2009, 74, 2846–2849.

14.

Yu Zhou, Enguang Feng, Guannan Liu, Deju Ye, Jian Li, Hualiang Jiang, and Hong Liu. Gold-Catalyzed One-Pot Cascade Construction of Highly Functionalized Pyrrolo[1,2-a]quinolin-1(2H)-ones. J. Org. Chem. 2009, 74, 7344–7348.

13.

Guannan Liu, Yu Zhou, Deju Ye, Dengyou Zhang, Xiao Ding, Hualiang Jiang, and Hong Liu. Silver-Catalyzed Intramolecular Cyclization of o-(1-Alkynyl)benzamides: Efficient Synthesis of (1H)-Isochromen-1-imines. Adv. Synth. Catal. 2009, 351, 2605–2610.

12.

Deju Ye, Xu Zhang, Yu Zhou, Dengyou Zhang, Lei Zhang, Hengshuai Wang, Hualiang Jiang, and Hong Liu. Gold- and Silver-Catalyzed Intramolecular Hydroamination of Terminal Alkynes: Water-Triggered Chemo- and Regioselective Synthesis of Fused Tricyclic Xanthines. Adv. Synth. Catal. 2009, 351, 2770–2778.

11.

Xiao Ding, Deju Ye, Fang Liu, Guanghui Deng, Guannan Liu, Xiaomin Luo, Hualiang Jiang, and Hong Liu. Efficient Synthesis of alpha-Aryl-/Heteroaryl-Substituted beta-Amino Acids via Ni(II) Complex through the Suzuki Coupling Reaction. J. Org. Chem. 2009, 74, 5656–5659.

10.

Deju Ye, Wenfeng Liu, Dengyou Zhang, Enguang Feng, Hualiang Jiang, and Hong Liu.  Efficient Dehydrative Sialylation of C-4-Aminated Sialyl-hemiketal Donors with Ph2SO/Tf2O. J. Org. Chem. 2009, 74, 1733–1735.

9.

Deju Ye, Jinfang Wang, Xu Zhang, Yu Zhou, Xiao Ding, Enguang Feng, Haifeng Sun, Guannan Liu, Hualiang Jiang, and Hong Liu. Gold-catalyzed intramolecular hydroamination of terminal alkynes in aqueous media: efficient and regioselective synthesis of indole-1-carboxamides. Green Chem. 2009, 11, 1201–1208.

8.

Deju Ye, Jiang Wang, Kunqian Yu, Yu Zhou, Hualiang Jiang, Kaixian Chen, and Hong Liu. Current Strategies for the Discovery of K(+) Channel Modulators. Curr. Top. Med. Chem. 2009, 9, 348–361.

2008
7.

Deju Ye, Jian Li, Jian Zhang, Hong Liu, and Hualiang Jiang. Simultaneous stereoselective 4-amination with cyclic secondary amines and 2-O-deacetylation of peracetylated sialic acid derivatives. Tetrahedron Lett. 2007, 48, 4023–4027.

6.

Guanghui Deng, Deju Ye, Lingyan He, Yu Zhou, Jiang Wang, Hualiang Jiang and Hong Liu. Synthesis of (S)-, (R)- and (rac)-2-amino-3,3-bis(4-fluorophenyl)propanoic acids and an evaluation of the DPP IV inhibitrory activity of denagliptin diastereomers. Tetrahedron 2008, 64, 10512–10516.

5.

Deju Ye, Guanghui Deng, Wenfeng Liu, Yu Zhou, Engguang Feng, Hualiang Jiang, and Hong Liu. Simultaneous 2-O-Deacetylation and 4-Amination of Peracetylated Neu5Ac: Application to the Synthesis of (4→4)-Piperazine Derivatives Linked Sialic Acid Dimers. Tetrahedron 2008, 64, 6544–6550.

2007
4.

Mingfang Zheng, Mingyue Zheng, Deju Ye, Yangmei Deng, Shuifeng Qiu, Xiaomin Luo, Kaixian Chen, Hong Liu, and Hualiang Jiang. Indole derivatives as potent inhibitors of 5-lipoxygenase: Design, synthesis, biological evaluation, and molecular modeling. Bioorg. Med. Chem. Lett. 2007, 17, 2414–2420.

3.

Zhiyi Yao, Deju Ye, Hong Liu, Kaixian Chen, and Hualiang Jiang. Transformation of aryl acyloin O-alkyl and O-phenyl derivatives to ketones. Synth. Commun. 2007, 37, 149–156.

2.

Deju Ye, Xiaomin Luo, Jianhua Shen, Weiliang Zhu, Xu Shen, Hualiang Jiang, and Hong Liu. Discovery potential drug leads via docking, synthesis and bioassay. Progress in Chemistry 2007, 19, 1939–1946.

2006
1.

Yuan Huang, Deju Ye, Qing Sun, Jianyi Shen. Surface modification and characterization of vapor grown carbon fibers. Chin. J. Inorg. Chem. 2006, 22, 403–410.