Image story

Cryo-SEM of in situ assembling nanoparticles on a cell surface

We have demonstrated that a small molecule probe, can be triggered by ALP expressed on HeLa cell surfacen, to form spherical nanoparticles anchored on the cell surface via a in situ self-assembly process. The in situ formed nanoparticles were clearly observed using cryo-SEM and TEM. More stroy, please read the paper entitled "Activatable NIR Fluorescence/MRI Bimodal Probes for in Vivo Imaging by Enzyme-Mediated Fluorogenic Reaction and Self-Assembly" that has been published in JACS on June 7. https://doi.org/10.1021/jacs.9b03649

Address: Rm D307, School of Chemistry and Chemical Engineering,

Nanjing University,163 Xianlin Rd, Nanjing, P. R. China

Phone: 86-25-89681905

E-mail:dejuye@nju.edu.cn

Powered by Weicheng