News

Our First Publication is Online!

发布时间:2017-08-21 

The invited contribution to Chemical Society Reviews (IF = 38.618) is online, “The Recent Achievements of Redox-Neutral Radical C-C Cross-Coupling Enabled by Visible-Light'', congratulations to Jin! This is our first paper at NJU.

     

Abstract: Visible-light photoredox catalysis has been esteemed as one sustainable and attractive synthetic tool. In the past four years, a new yet challenging trend, visible-light-driven redox-neutral radical C–C crosscoupling involving putative radical intermediates, has been booming rapidly. Its advent brings a powerful platform to achieve non-classical C–C connections, and should lead to fundamental changes in retrosynthetic analysis. In this tutorial review, we highlight the recent achievements of visible-light-mediated redox-neutral radical C(sp3 )–C(sp2 ), C(sp3 )–C(sp), and C(sp3 )–C(sp3 ) bond formation, opening a new window for C–C cross-coupling through the photoredox electron shuttling cycle between two coupling partners. While radical–radical coupling steered by the persistent radical effect was proposed as a rational explanation for the redox-neutral photoredox events, alternative kinetically driven chain propagation and radical addition pathways cannot be ruled out. This tutorial review aims to highlight the recent achievements of photoredox-neutral radical C–C coupling in synthetic chemistry.

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